Michelle Rodriguez will reprise her role as Rain, the character was killed off in the first Resident Evil movie in Paul W.S. Anderson's Resident Evil: Retribution, the upcoming fifth installment of Sony Pictures' popular Resident Evil franchise which is scheduled to hit theaters on September 14th, 2012. Colin Salmon is returning as One. Resident Evil: Retribution will feature the Las Plagas parasite. Las Plagas are a breed of parasitic organisms in the Resident Evil games. Unlike the t-virus, which turned its victims into mindless zombies, the victims of Las Plagas become much stronger and highly resistant to pain, while working collectively to pursue their targets. Rodriguez & Salmon co-star with Milla Jovovich, Sienna Guillory & Shawn Roberts. Screen Gems & Sony Pictures have scheduled Resident Evil: Retribution, which is currently filming in Toronto, Canada, for theatrical release on September 14th, 2012. Bloody-Disgusting broke the story.