Sam Rockwell [Moon] is in negotiations to star opposite Jennifer Garner in Occupant Films' Better Living Through Chemistry according to Variety. The site states that "Rockwell will play a meek, small-town pharmacist stuck in a loveless marriage who rediscovers himself by starting an affair with a trophy wife [Garner.] After she introduces him to the pleasures of prescription drugs, things spin out of control when they begin plotting to kill her husband." Rockwell would be replacing a previously cast Jeremy Renner in the role. Michelle Monaghan [Kiss Kiss Bang Bang] will play Rockwell's wife, while Judi Dench is narrating. Geoff Moore and David Posamentier will be making their directorial debut from their original script.